Researchers from the University of Alberta have investigated factors which contribute to the deviation of a normal infant gut microbiome and how these deviated gut microbiomes may have the ability to predict future health including food allergies. Significance analysis of microarrays (SAM) was used to quantify the gut microbial abundance of infants over time, specifically exploring factors of birth mode (cesarean section or vaginal delivery), feeding status (breastfed or formula-fed), and antibiotic exposure.
Please join on Friday October 27, 2017 from 3:00 to 4:00PM in HSC 3N10A as we will discuss:
1. What is perceived as a normal infant gut microbiome?
2. What is SAM and what are the strengths and weaknesses of using SAM in analysis?
3. Could other mechanism be used to study microbial community development over time?
Yasmin, F. et. al. (2017). Cesarean Section, Formula Feeding, and Infant Antibiotic Exposure: Separate and Combined Impacts on Gut Microbial Changes in Later Infancy. Frontiers in Pediatrics, 5, 200. http://doi.org/10.3389/fped.2017.00200