Author Archives: jamesstpierre

2 for 1 deal: a response to Waste Not, Want Not and the benchmarking of ANCOM

This week’s microbiome journal club will look at the recent paper by Rob Knight’s group (Weiss et al., 2017) that simultaneously responded to “Waste Not, Want Not” and confirmed ANCOM as an effective differential abundance analysis technique.  More details about … Continue reading

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What is the most appropriate method for associating microbiome data with health and disease?

As DNA-sequencing technologies became cheaper to use, profiling the microbiomes of many different samples became efficient and feasible through the sequencing of highly variable regions on the bacterial 16S rRNA gene. A question that arises very quickly to novices in … Continue reading

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