Category Archives: Talks

2in1: Assembly benchmarking and evaluation

The numbers of metagenomics studies are exponentially increasing in recent years. Because we lack comprehensive microbial genome databases for most environments, the microbiome field is moving towards de novo metagenomics, using reference-independent techniques to assemble putative genes and in silico refinement of … Continue reading

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Can the development of the gut microbiome of infants impact their future health?

Researchers from the University of Alberta have investigated factors which contribute to the deviation of a normal infant gut microbiome and how these deviated gut microbiomes may have the ability to predict future health including food allergies. Significance analysis of … Continue reading

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Reminder: HMJC This Week!

Just a little reminder that the Human Microbiome Journal Club is meeting, unusually, this week! We’ll be discussing Gloor & Reid and compositional data analysis in HSC 3N10A at 3 p.m. on Friday, September 15. Check out the original post … Continue reading

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September journal club moved to Friday, September 15

Please note that the September Human Microbiome Journal Club has been rescheduled to Friday, September 15 at 3 p.m.

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September 15: Gloor & Reid’s Compositional Data Analysis

This month’s Human Microbiome Journal Club has been cancelled due to an outbreak of vacationitis, but we will resume next month on Friday, September 15 at 3 p.m. in HSC 3N10A. At the end of September, we’ll be discussing Gloor … Continue reading

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The Microbiome and Longevity: How gut microbes may impact lifespan

In recent years, the microbiome has been recognized as a major factor affecting the functioning of host organisms, influencing both health and disease. At the same time, aging research has provided many possible interventional strategies aimed at extending the human … Continue reading

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2 for 1 deal: a response to Waste Not, Want Not and the benchmarking of ANCOM

This week’s microbiome journal club will look at the recent paper by Rob Knight’s group (Weiss et al., 2017) that simultaneously responded to “Waste Not, Want Not” and confirmed ANCOM as an effective differential abundance analysis technique.  More details about … Continue reading

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So you want to be a MicrobiomeAnalyst?

Analysis of microbiota composition has been an ongoing pursuit for decades. However, the improved feasibility of next-generation sequencing techniques have greatly increased access to gigabytes of microbiome data. Whether you look at the hypervariable regions of bacterial 16S rRNA gene … Continue reading

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Get That Weak Staph Outta Here!

Certain skin commensal bacteria protect individuals against Staphylococcus aureus colonization We’re all covered in skin (hopefully) and our skin is covered with microbes. For the most part, this skin microbiome coexists with us and remains stable, despite our constant contact with other people and our environment. … Continue reading

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Genomes from metagenomics: pulling the needles from the haystack.

Shotgun whole genome sequencing revolutionized how we study single, microbial isolates. By breaking the genome into small reads in vitro, we are able to parallelize sequencing and decrease costs before bioinformatic assemblers put the puzzle back together again in silico. However, re-building the genomic … Continue reading

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